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New York funding

A Humanized Monoclonal Fsh Blocking Antibody For Alzheimer's Disease - Project Summary Alzheimer’s Disease (ad) Stands…

$10.6M

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Funder
Department of Health and Human Services
Amount
$10.6M
Recipient
Icahn School Of Medicine At Mount Sinai
Deadline
Through August 31, 2027

Purpose

Department of Health and Human Services awarded $10.6M to Icahn School Of Medicine At Mount Sinai for A humanized monoclonal fsh blocking antibody for alzheimer's disease - project summary alzheimer’s disease (ad) stands out as notable in not having a cure among many diseases that affect elderly men and women––in essence, creating an urgent need for a new therapy. it is also unclear why menopausal women have a preponderance of ad, and, while declining estrogen bas been implicated, there is clear clinical correlation with rising levels of follicle stimulating hormone (fsh). we have identified fsh as a target for several aging disorders––osteoporosis, obesity, hypercholesteremia––and now, ad. inhibiting the action of fsh using blocking antibodies reduces body fat, increases bone mass,…

federalusaspendinggranthealthny

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